Bordeaux University hospital – Stroke Unit
Pr Sibon will contribute to the development of the covert cerebral small vessel clinic, recruitment and evaluation of patients and management of clinical trials dedicated to reduce the cognitive burden of covert cerebral small vessel disease and the risk of symptomatic cerebro-vascular events.
Neurology Neurovascular Stroke
|Institution and location
|Field of study
|Medical studies- Neurology
|2000 - 2004
|Molecular mechanisms of intracranial artery structural integrity: role of amine oxydases
|Mc Gill University (Canada)
|2004 - 2006
|Molecular imaging in psychiatric disorders
|Title/Institution or Organization/Country
|Professor of Neurology (PUPH) at Bordeaux University Hospital -FRANCE
|From 2006 to 2009
|Associates Professor (PHU) at Bordeaux University Hospital- FRANCE
|From 2004 to 2006
|Research fellow at McGill University-Qc-CANADA
|From 2000 to 2004
|Clinical fellow Bordeaux Hospital- FRANCE
President of the French Neurovascular Society
Fukutomi H, Yamamoto T, Sibon I… Tourdias T.
Location-weighted versus Volume-weighted Mismatch at MRI for Response to Mechanical Thrombectomy in Acute Stroke. Radiology. 2022. doi: 10.1148/radiol.220080
Demonstrates the improvement of the identification of patients with acute stroke who would benefit from mechanical thrombectomy using location-weighted infarction core and mismatch on diffusion and perfusion MRI scans compared with the volume-based target mismatch profile.
Provides algorithms based on a step-by-step approach for anticoagulant reversal in patients presenting with stroke.
Suggests that cerebral SVD is independently associated with functional, cognitive, and psychological outcomes, but had no clinically relevant added value to predict the individual outcomes of patients when compared to the usual predictors, such as age and baseline NIHSS.
Suggests that prior antiplatelet therapy does not influence angiographic and functional outcomes following endovascular therapy in acute ischemic stroke.
Sagnier S, (…), Debruxelles S, Poli M, Olindo S, Renou P, Rouanet F, (…), Sibon I.
Normal-Appearing White Matter Integrity Is a Predictor of Outcome After Ischemic Stroke. Stroke. 2020. doi: 10.1161/STROKEAHA.119.026886
Identifies NAWM diffusion tensor imaging parameters measured early after an ischemic stroke as independent predictors of functional outcome.
Suggests that a high load of cortical cerebral microinfarcts in patients with stroke can be considered as a cerebral frailty condition which counteracts to the recovery process, suggesting a reduced brain plasticity among these patients.
Kuchcinski G, … Sibon I, Tourdias T.
Thalamic alterations remote to infarct appear as focal iron accumulation and impact clinical outcome. Brain. 2017. doi: 10.1093/brain/awx114.
Identifies iron accumulates within the thalamus ipsilateral to infarct after a delay with a focal distribution that is strongly linked to the initial infarct location and independently contributes to functional, cognitive and emotional outcome.