University of Bordeaux / INSERM UMR 1219 Population Health Research
Research Institute for Sustainable Development (IRD) EMR 271, Bordeaux
Co-PI of work package 5 / IHU
None Communicable Diseases Global South Epidemiology Clinical research
|Institution and location
|Field of study
|Title/Institution or Organization/Country
|07/2011 – 11/2022
|ADERA Pessac, France
|11/2007 – 06/2011
|University of Bordeaux, France
IeDEA West African Database on Antiretroviral Therapy
The aims are to conduct hypothesis-driven epidemiological research on the prognosis and outcome of HIV type 1 and 2 infected people, including adults, pregnant mothers, and children. The West Africa Data Base on Antiretroviral Therapy Collaboration is a network of treatment cohorts in West Africa. https://www.iedea.org/regions/west-africa/
Role: PI/program director
The AIMA-CC study
The aim of the study is to evaluate several “triage” algorithm following a primary cervical cancer screening based on self-sampled HPV testing in HIV-infected women followed in Cote d’Ivoire and Burkina Faso.
The aim of this project was to assess the feasibility for the initiation of a cohort of patients chronically infected with Hepatitis B virus in Senegal
Scholarship from “Fondation pour la Recherche Medicale”
Young Investigator Award - 18th Conference on Retroviruses and Opportunistic Infections (CROI), Boston, USA
Chronic viral hepatitis, HIV infection and Non-Hodgkin lymphomas in West Africa, a case-control
Jaquet A, Boni SP, Boidy K, Tine J, Tchounga B, Touré SA, Koffi JJ, Dial C, Monnereau A, Diomande I, Tanon A, Seydi M, Dabis F, Diop S, Koffi G; IeDEA West Africa Collaboration. Int J Cancer. 2021 doi: 10.1002/ijc.33709.
While hepatitis B virus (HBV) infection is positively associated with non-Hodgkin lymphoma (NHL) in some regions of the world, whether HBV increases risk of NHL remains uncertain. In this case-control study based on data from referral hospitals in sub-Saharan Africa, the authors describe a significant association between HBV infection and NHL. In West Africa, NHL was significantly associated with chronic infection with HBV and hepatitis C virus (HCV). The findings suggest that the implementation of measures to prevent HBV infection, along with efforts to ensure access to anti-HCV treatments, could greatly reduce NHL in settings with high HBV prevalence.
Etiology of hepatocellular carcinoma in West Africa, a case-control study.
Jaquet A, Tchounga B, Tanon A, Bagny A, Ekouevi DK, Traore HA, Sasco AJ, Maiga M, Dabis F. Int J Cancer. 2018 doi: 10.1002/ijc.31393.
Liver cancer represents a leading cause of cancer-related mortality in West Africa. While hepatitis B virus has been previously identified as the major contributor to liver cancer in this endemic region, limited information is available on other risk factors. Here, the authors conducted a case–control study in hospitals in Côte d'Ivoire, Mali and Togo. Aside the independent association of alcohol use and HBV and HCV infection with liver cancer, a synergic effect between alcohol use and HBV infection was identified. Timely screening and care of HBV infection and hazardous drinking might significantly curb HCC in West Africa.
Alcohol use, viral hepatitis and liver fibrosis among HIV-positive persons in West Africa: a cross-
Jaquet A, Wandeler G, Nouaman M, Ekouevi DK, Tine J, Patassi A, Coffie PA, Tanon A, Seydi M, Attia A, Dabis F. J Int AIDS Soc. 2017 doi: 10.7448/IAS.20.1.21424.
Liver diseases, leading to cirrhosis and ultimately liver failure or hepatocellular carcinoma is now a major cause of death worldwide but there is limited information on the burden of liver fibrosis/cirrhosis from sub-Saharan Africa. Through its network of observational cohorts in West Africa, the IeDEA collaboration has been a pioneer in the implementation of none-invasive assessment of liver fibrosis/cirrhosis through transient elastography in sub-Saharan Africa, assessing the relative contribution of HBV and HCV on liver disease in HIV-infected populations.
Hepatitis B treatment eligibility in West Africa: Uncertainties and need for prospective cohort
Jaquet A, Nouaman M, Tine J, Tanon A, Anoma C, Inwoley A, Attia A, Ekouevi DK, Seydi M, Dabis F, Wandeler G. Liver Int. 2017. doi: 10.1111/liv.13484.
We provided one of the few contributions on the proportion of HBV-infected patients eligible to antiviral therapy in sub-Saharan Africa, a crucial key indicator to achieve the WHO 2030 target for HBV elimination.
Assessment of the scale-up of cervical cancer screening in Abidjan stratified by HIV status.
Boni S, Tchounga B, Comoe K, Guie P, Adié M, Horo A, Messou E, Ekouévi DK, Dabis F, Adoubi I, Jaquet A. Int J Gynaecol Obstet. 2019. doi: 10.1002/ijgo.12959.
A report of successes and challenges of scaling up a population-based cervical cancer (CC) screening program from HIV clinics to various healthcare facilities in Abidjan, Côte d'Ivoire. At a population level, despite successful expansion of cervical cancer screening from HIV clinics to other healthcare facilities, screening coverage of the targeted population remains low in Abidjan, far from the WHO 2030 target for cervical cancer elimination.